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What should my health care professional know before I take Esomeprazole? Nexium is used to treat the infection, which is responsible for the majority of gastric ulcers. Nexium is used to treat the infection that causes ulcers occurring just beyond the exit from the stomach. Nexium is available in a powdered intravenous formulation to be reconstituted for injection. Nexium decreases the amount of acid backing up into the esophagus and causing reflux symptoms. Because Nexium is likely to appear in breast milk you will need to choose between taking Nexium or breastfeeding your baby. Nexium is the newer formulation of the original Omeprazole product - both prescription drugs used to treat the infection, which is responsible for the majority of gastric ulcers. Because Nexium is likely to appear in breast milk you will need to choose between taking Nexium or breastfeeding your baby.