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Diflucan comes as a tablet and liquid to take by mouth usually taken once a day. Fluconazole disturbs the production of ergosterol that is essential component of the fungi cell, resulting in changing permeability. Diflucan is usually taken by mouth as a one-time only dose with or without food or as directed by your doctor. Fluconazole works best if it is taken at the same time each day. In the fungal infection Cryptococcus.
