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Patients taking other cephalosporin antibiotics can not take additional cephalosporin antibiotics as this is likely to result in an overdose. Patients with known allergy to the cephalosporin group of antibiotics. It's important to take the full dosage schedule of Keflex, even if you're feeling better in a few days. Take Keflex at even intervals around the clock as prescribed by your doctor. Additional antibiotics should be avoided entirely while you are taking Cephalexin.